ESMO Breast Cancer. Invitation to Industry BERLIN GERMANY 2-4 MAY Annual Congress

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ESMO Breast Cancer Invitation to Industry Annual Congress BERLIN GERMANY 2-4 MAY 2019 ESMO Breast Cancer, a multidisciplinary global meeting held in Europe, involving the top worldwide recognised experts, is the platform for all Breast Cancer researchers and clinicians with a specific interest in innovation, translational oncology and care. esmomeetings.org

WELCOME Dear Industry Partners, We have the extraordinary privilege to invite you to ESMO Breast Cancer, an annual congress taking place for the first time from 2 to 4 May 2019 in Berlin, Germany. Cancer patients and their needs are at the heart of what we do we are dedicated to advancing research and integrating it into the clinic to ensure better care for our patients. In recent years, we have seen remarkable progress in treatment options and improved outcomes for breast cancer patients. We are committed to delivering a comprehensive overview of all the practice-changing new data and making sure it has a clear roadmap to the clinic to improve care for patients. Brought to you by ESMO, your trusted provider of specialised education in oncology, the congress is designed by the world s foremost experts in breast cancer. Your support will be invaluable to us as we work on the first edition of this very special meeting. It offers you a variety of well-designed opportunities to share data, present innovation and interact with key stakeholders in breast cancer. By supporting ESMO Breast Cancer 2019 you have the opportunity to: Gain insights into the most promising drug development avenues Present your latest research at a meeting founded by ESMO: a guarantee for immediate global visibility Connect with a wide multidisciplinary audience of breast cancer specialists and stakeholders Present your offer at an exciting new forum in a major European city Re-present your key data at ESMO Asia We look forward to working with you towards a very successful first edition of ESMO Breast Cancer! Giuseppe Curigliano Milan, Italy Co-Chair Sibylle Loibl Neu-Isenburg, Germany Co-Chair 2

INVITATION TO INDUSTRY TARGET AUDIENCE The ESMO Breast Cancer 2019 congress is designed for breast cancer researchers and clinicians who have a specific interest in innovation (including translational research, new agents, molecular and functional diagnostics, biomarkers and cutting-edge research applications in the clinical setting) and care. It will be a multidisciplinary European Meeting involving top scientists. LEARNING OBJECTIVES The 2019 programme features sessions on innovative treatments, DNA damage, early clinical opportunities, immunotherapy and breast cancer response, metabolism, regulation of breast cancer diversity, and resistance to targeted therapy. These topics span basic, clinical, epidemiologic, prevention, and translational research areas that have implications for treatment now and in the future. Learning objectives: To advance knowledge To integrate translational research into cancer care To further improve precision medicine To disseminate education To improve the practice of breast cancer specialists worldwide. SPONSORING AND GRANTS Corporate as well as non-profit entities committed to improving systemic cancer therapy are invited to support this congress by providing financial contributions. The BREAST organising committee welcomes contribution in the following categories: Unrestricted educational grants Sponsoring arrangements - Sponsorship packages - Stand-alone sponsor benefits For any information regarding educational grants or sponsorship opportunities please contact: Jon Roberts Head of Strategic Partnerships +44 (0) 7932 6779 11 jon.roberts@esmo.org 3

PRELIMINARY PROGRAMME PREVIEW MARITIM HALL Plenary 700-1700 theatre 13:30-13:45 Opening 13:45-14:15 Keynote and Award THURSDAY 2 MAY 2019 BERLIN HALL 400-650 theatre 11:30-12:00 12:00-13:00 Satellite Symposium 1 13:00-13:30 Welcome reception VIENNA HALL 200 theatre 11:30-12:00 12:00-13:00 Satellite Symposium 2 RIGA HALL 200 theatre 14:30-16:00 Educational 1 Early breast cancer: HER2 positive 14:30-16:00 Educational 2 Translational Oncology 14:30-16:00 Proffered papers 1 14:30-16:00 Nursing session EONS 1 16:00-16:30 Coffee break 16:30-18:00 Educational 3 Early breast cancer: HER2-/HR positive 16:30-18:00 Educational 4 Selection of high risk /low risk patients 16:30-18:00 Poster Discussion 1 16:30-18:00 Nursing session EONS 2 18:00-18:30 18:00-18:30 18:00-18:30 18:30-19:30 Satellite Symposium 3 18:30-19:30 Satellite Symposium 4 18:30-19:30 Satellite Symposium 5 19:30-20:00 19:30-20:00 19:30-20:00 4

INVITATION TO INDUSTRY MARITIM HALL Plenary 700-1700 theatre FRIDAY 3 MAY 2019 BERLIN HALL 400-650 theatre 07:45-08:30 ELDERLY with SIOG and EORTC VIENNA HALL 200 theatre RIGA HALL 200 theatre 07:45-08:30 YO Meet the Prof 1 08:45-10:15 Educational 5 Early breast cancer: TNBC 08:45-10:15 Proffered papers 2 08:30-09:30 Controversy 1 Platinum agents 08:45-10:15 Patient Advocates session 09:45-10:15 Prevention/Epidem Educational 6 Immuno-oncology 14:10-14:40 Keynote 2 14:45-16:15 Multidisc. Tumour Board Pre-menopausal women with early & metastatic breast cancer 16:45-18:15 Proffered Papers 3 Best abstracts Educational 7 Personalised medicine 13:00-14:00 Satellite Symposium 6 14:00-14:15 10:15-10:45 Coffee break 12:15-13:00 Poster lunch 16:15-16:45 Coffee break Educational 8 Metastatic breast cancer: HER2 positive 13:00-14:00 Satellite Symposium 7 14:00-14:15 BC in Young Women 13:00-14:00 Satellite Symposium 8 14:00-14:15 18:20-18:30 18:30-19:30 Satellite Symposium 9 19:30-20:00 18:20-18:30 18:30-19:30 Satellite Symposium 10 19:30-20:00 18:20-18:30 18:30-19:30 Satellite Symposium 11 19:30-20:00 5

MARITIM HALL Plenary 700-1700 theatre 08:45-10:15 Educational 9 Metastatic breast cancer: HER2-/HR positive SATURDAY 4 MAY 2019 2019 BERLIN HALL 400-650 theatre 08:45-10:15 Poster Discussion 2 10:15-10:45 Coffee break VIENNA HALL 200 theatre 08:30-09:30 Controversy 2 Multigene testing in early & metastatic breast cancer 09:45-10:15 Spotlight 2 RIGA HALL 200 theatre 07:45-08:30 YO Meet the Prof 2 08:45-10:15 Patient Advocates session Educational 10 Metastatic breast cancer: TNBC Educational 11 Radiation therapy Educational 12 Innovative treatment across subtypes Educational 13 Surgery 12:15-12:30 12:15-12:30 12:30-13:30 Satellite Symposium 12 12:30-13:30 Satellite Symposium 13 13:30-14:00 13:30-14:00 6

INVITATION TO INDUSTRY UNRESTRICTED EDUCATIONAL GRANTS Educational grants will be used to defray the costs of the congress as an educational activity. Unrestricted educational grants of 20 000 or above are welcome. Donors will be acknowledged pre- and postcongress under the heading Unrestricted educational grants : On the congress website from the date of booking until 6 months after the congress By slide projection of corporate logo/company name in the lecture hall during void moments of the programme By corporate logo/company name on banners at the congress venue All educational grants include the following benefits: Two (2) full delegate registrations 7

SPONSORSHIP PACKAGES PLATINUM SPONSOR 100 000 One 60-minutes satellite symposium slot, assigned by level of sponsorship and on a first come, first served basis Exhibition space between 24-30 sqm, chosen on a first come, first served basis 20 full delegate registrations 4 seats at the speaker dinner Two delegate-bag inserts Advertisement in the programme book - One outside back cover or alternative prime position Company acknowledged as Platinum Sponsor at the ESMO Breast Cancer congress, as follows: - In the congress programme book - On inter-session slides in the congress room - On the congress website - In the 2 general sponsor banners at the congress venue Additional 60-minute satellite symposium slot, available upon request at the rate of 30 000 GOLD SPONSOR 70 000 One 60-minutes satellite symposium slot, assigned by level of sponsorship and on a first come, first served basis Exhibition space between 18-24 sqm, chosen on a first come, first served basis 10 full delegate registrations 2 seats at the speaker dinner One delegate-bag insert Advertisement in the programme book - One internal full page Company acknowledged as Gold Sponsor at the ESMO Breast Cancer congress, as follows: - In the congress programme book - On inter-session slides in the congress room - On the congress website - In the 2 general sponsor banners in the congress venue Additional 60-minute satellite symposium slot, available upon request at the rate of 30 000 SILVER SPONSOR 40 000 Exhibition space between 12-18 sqm, chosen on a first come, first served basis 5 full delegate registrations 1 seat at the speaker dinner One delegate-bag insert Advertisement in the programme book - One internal full page Company acknowledged as Silver Sponsor at the ESMO Breast Cancer congress, as follows: - In the congress programme book - On inter-session slides in the congress room - On the congress website - In the 2 general sponsor banners in the congress venue BRONZE SPONSOR 20 000 Exhibition space between 6-9 sqm of Standard shell scheme booth: - Including booth construction and signage (company name), carpet and power; excluding furniture and other technical facilities - Companies/organizations wishing to exhibit will receive the exhibition floorplan with availability of space at the time of reservation 2 full delegate registrations Company acknowledged as Bronze Sponsor at the ESMO Breast Cancer congress, as follows: - In the congress programme book - On inter-session slides in the congress room - On the congress website - In the 2 general sponsor banners in the congress venue SUPPORTER 7 500 2 full delegate registrations Company acknowledged as Supporter at the ESMO Breast Cancer congress, as follows: - In the congress programme book - On inter-session slides in the congress room - On the congress website - In the 2 general sponsor banners in the congress venue 8

INVITATION TO INDUSTRY ADDITIONAL SPONSORSHIP OPPORTUNITIES Congress mobile application 10 000 Congress participants can download the Final Programme both before and during the congress via their mobile devices and receive ongoing information about the congress. Sponsor s logo on the congress website Signage on-site with acknowledgment of the sponsor as the supporter of the mobile application Welcome message from the supporter upon login to the application 2 promotional messages will be integrated into the mobile application with notes from the sponsor Business Rooms 4 000-6 000 Platinum and Gold sponsors can apply for a business room, located in the congress venue, on a first come, first served basis. Business rooms (available for informal and non-commercial talks) can be rented for the full duration of the congress and have a surface between 50-100 sqm. Travel grant support per 5 fellows 6 000 Acknowledgement as supporter of authors under the age of 40, who are presenting abstracts 1 grant consists in: 3 nights accommodation, a full registration to the congress, 600 contribution to travel Speaker Preview Centre 2 000 Higher visibility with key opinion leaders Networking and reinforcement with our elite key opinion leaders Logo would be indicated as support of the Speaker Preview Centre s permanent coffee breaks and technical equipment s Insert in congress bags 2 000 An insert, provided by the sponsor, in all delegate bags Inserts may be flyers, booklets, CDs, journal samples, small give-away items Content of the insert is subject to pre-approval by congress organizers Sponsor fee includes handling of inserts from the point of delivery to congress organizers Congress Bags 9 000 Exclusive grant to support a bag for all congress delegates Bags will feature the sponsor s corporate logo on a luggage tag Sponsor may include one give-away item in the congress bag Choice of bag and supplier at the discretion of the congress organizers Notepads 3 000 Organizers produce notepads for congress bags featuring the sponsor s logo Pens 3 000 Organizers produce pens for congress bags featuring the sponsor s logo Advert in the programme book 3 000 Improve your visibility and reinforce your congress take-home message by placing an advertisement in the programme book. The ESMO Breast Cancer programme book is available to all participants. Welcome reception 8 000 Exclusive grant to support the welcome reception The reception is open to all delegates; complimentary beverages and light snacks served Featured recognition with corporate logo in the Welcome reception area Selection of beverages and catering at the discretion of congress organizers Coffee Break 2 500 (per break) Exclusive sponsorship of the coffee breaks on one day of the congress Featured recognition with corporate logo on a banner in the coffee service area Promotional messages on mobile application 2 000/ message A promotional message will be integrated into the mobile application with a note from the sponsor. The sponsor can promote their symposium/booth/product via the promotional messages. Important Information Other sponsorship opportunities are available on request. We are open to your suggestions and can help you to select the best sponsorship activities to suit your marketing target and strategies 9

AGREEMENT RULES AND CONDITIONS The following conditions of participation refer to the booking of any sponsorship product(s)/service(s) at the ESMO Breast Cancer 2019 insofar as the contractual partners do not reach contrary agreements in writing. Establishment of Contract Application for a sponsorship product(s)/service(s) is made by filling in and returning the sponsorship application form to ESMO. Only completed and signed application forms will be taken into consideration. By signing the sponsorship application form, the company accepts the conditions contained in the ESMO Breast Cancer 2019 Industry Guidelines and any supplementary provisions. Confirmation of the allocation of any sponsorship product(s)/ service(s) by ESMO in writing constitutes establishment of contract between the sponsoring company and ESMO. An invoice will then be sent by registered mail. The date of the assignment is considered to be the date of allocation. If the contents of the assignment deviate from the contents of the sponsoring company s application, the contract is based on the assignment issued by ESMO unless the company objects in writing within two weeks after the date the assignment was sent. Appointed Agencies Application for any sponsorship product(s)/service(s) must be submitted by the sponsoring company under whose name each sponsorship item is to be listed. Correspondence in this regard must be made exclusively between the sponsoring company and ESMO. Sponsoring companies should inform ESMO in writing which agency is appointed. Otherwise no request from agencies will be taken into consideration. It is not the role of any given agency to make initial enquiries or reservations with ESMO independently of the sponsoring company. The sponsoring company is responsible for communicating these regulations to its staff and its appointed agencies. This named agency cannot fully act as if it were the sponsoring company itself and the sponsoring company will continue to be held entirely responsible and accountable for activities organised in its name. Procedure Send the sponsorship application form to ESMO Strategic Partnership department, who will acknowledge receipt of your sponsorship application form and the assignment process will commence soon afterwards. Assignment Will be done on a first come, first served basis (excluding the satellite symposia assignments). To ensure each sponsoring company has a chance to choose a suitable stand and satellite symposium slot, offers are valid for 48 hours (2 working days) unless the offer makes it clear that the opportunity is freely available. For this reason, please supply a reliable contact telephone number for an appropriate decision maker within the company. Payment deadlines Assignments will be cancelled automatically if the related cost has not been paid within the given time period. In such cases the cancellation fee will be applicable following the cancellation policy. Terms of Payment Payment is due within 30 days following the date of the invoice. Cancellation Policy The company cancelling its support after the official application has been accepted and the corresponding sponsorship package has been assigned will be liable to a 100% cancellation fee. Administration fees/invoicing changes Invoices will be addressed according to the invoicing data provided by the sponsoring company. Please note, if a billing change is requested (i.e. company name change or address change), an administration fee of 70 EUR (Excluding VAT) will be charged to the company. Indebtedness Payments not received by the first day of the start of the ESMO Breast Cancer 2019 will be subject to a 10% penalty fee on the total sponsorship investment. Refunds Any refunds of deposits paid will be made after ESMO Breast Cancer 2019 but not later than the 31 December 2019. The sponsoring company will not be entitled to any interest that the organiser may have derived from deposits made. All bank charges, including sender s and receiver s charges, resulting from a refund related to cancellation or reduction of sponsorship will be at the charge of the sponsoring company. 10

INVITATION TO INDUSTRY Postponement or Abandonment ESMO reserves the right to postpone the event including the exhibition, or to transfer it to another site, if unforeseen circumstances warrant such action. Should any contingency prevent the holding of the ESMO Breast Cancer 2019 or any of its parts, ESMO cannot be held liable for any costs, expenses and damages (including, but not limited to direct or consequential damages, loss of opportunity, loss of use, or loss of revenue or profit) incurred in connection with the postponement or abandonment. Unexpected cancellation of the event: ESMO reserves the right to cancel without notice or compensation ESMO Breast Cancer 2019 in the event of force majeure cases (e.g. strikes, riots, fires, flood, terrorist attacks, governmental actions and regulations, damages or other fatal occurrences). In such cases, ESMO is not liable for failure to perform any obligation hereunder but will reimburse any payments received from the sponsoring company less any costs incurred while preparing the event. Limitation of Liability of ESMO ESMO shall not be liable for any damages, dispute or injury arising out of or in connection with the performance of this Agreement unless caused by wilful act, gross negligence or default of an employee, director, representative or contractor. Nor shall ESMO be liable to the sponsoring company for any indirect or consequential loss, damages, claims or demands arising out of this Agreement, including without limitation any economic loss or other loss of income, profits, business, opportunity, reputation or goodwill. Bankruptcy or Liquidation In case the sponsoring company becomes bankrupt or enters into liquidation other than for the purpose of restructuring or merger, or has a receiver appointed, ESMO shall be at liberty to terminate immediately the contract with the sponsoring company, to cancel the allocation of sponsorship product(s)/service(s) to the company and to forfeit all sums paid by the company. Security and Insurance Neither ESMO nor its contractors shall be responsible for the safety of any exhibit or other property of the sponsoring company or any person. Furthermore, ESMO nor its contractors shall be responsible for the loss, theft, damage or destruction by any cause of the exhibits or other property, or for loss, damage or injury sustained by any exhibits or any other persons. The sponsoring company/ exhibitor shall indemnify ESMO and its contractors to third persons, as a result of any act or omission of the company, its staff, agent or personnel hired on a temporary basis. As ESMO and its contractors will accept no responsibility for any of the foregoing matters, the sponsoring company should acquire their own insurance against any risk of loss due to theft or negligence, damage, injury or liability. The sponsoring company agrees not to pursue ESMO for any previously listed risks. Enforcement of Rules Applies equally to all. All companies investing in sponsorship at ESMO Breast Cancer 2019 must comply with all rules and policies established by ESMO. Violation Procedure The procedure for policing and enforcing the violation is as follows: When noticing a violation, ESMO staff will ask the company to correct the situation according to the applicable regulations. If the company refuses to comply, ESMO staff will report alleged violations to the congress Committee. After considering the available evidence, a representative of the relevant sponsoring company will be invited to present the company s view, after which the Committee will give its opinion. This will be confirmed in writing after ESMO Breast Cancer 2019. Appeals may be made to the ESMO Management. Penalties First violation: No accrual of points for the year. Second violation: No accrual of points plus the loss of all accrued points to date. Third violation: No right to participate at the next ESMO event. Claims Procedures, Place of Performance and Jurisdiction All claims by the company booking any sponsorship product(s)/ service(s) against ESMO must be in writing. The maximum time lapse is 1 month from the closure of ESMO Breast Cancer 2019. Agreements which deviate from these conditions or from the supplementary regulations must be in writing; facsimile signature suffices. The contract is governed exclusively by Swiss law; the English text is authoritative. Non-smoking policy ESMO Breast Cancer 2019 is a non-smoking event. Final Clause In cases not covered by the regulations in these General Terms and Conditions, ESMO interpretation shall be final 11

INVITATION TO INDUSTRY GENERAL INFORMATION Venue The congress will take place at the Maritim Hotel in Berlin, Germany. maritim.com Registration The registration fee includes access to the congress sessions, delegate bag and material, welcome reception. Accommodation Hotel rooms at the exceptional rate of 155 euro per night have been booked at the Maritim Hotel. In order to benefit from this special rate, bookings must be made via the direct link on the ESMO website. 30 January 2019 Abstract submission deadline 13 January 2019 Early registration 3 April 2019 LBA deadline 2-4 May 2019 Congress 3 April 2019 Late registration Jon Roberts Head of Strategic Partnerships +44 (0) 7932 677911 jon.roberts@esmo.org 12