Overview of Cancer Prevention and Research Institute of Texas

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Overview of Cancer Prevention and Research Institute of Texas (CPRIT) Funding HOUSE APPROPRIATIONS COMMITTEE PREPARED BY THE LEGISLATIVE BUDGET BOARD DECEMBER 20, 2012

Establishment and Creation of CPRIT CPRIT was established with the passage and ratification by voters of a constitutional amendment in November 2007 (House Joint Resolution 90, Eightieth i h Legislature, 2007); CPRIT is the successor agency to the Cancer Council; Amendment authorized $3 billion in general obligation bonds to fund grants for cancer prevention and research, and agency operations; Page 2

Article III, Section 67 & Health and Safety Code 102 Amendment also limits issuance of bonds, by the Texas Public Finance Authority on behalf of CPRIT, to no more than $300 million per fiscal year; CPRIT is governed by the Constitution & Statute: Art. III, Sec. 67 of the Texas Constitution includes the original amendment creating the agency and authorizing bond issuance. Health and Safety Code 102, CPRIT s enabling statute (HB 14, 80 th Legislature) provides: Sunset date of September 2021; Limits the amount of awards for prevention grants to 10 percent in any given fiscal year; and Establishes the Oversight Committee as CPRIT s governing body. Page 3

Oversight Committee CPRIT is governed by an Oversight Committee which consists of 11 members composed of three appointees each from the Governor, Lieutenant Governor, and Speaker of the House of Representatives. Additionally, both the Comptroller and Attorney General, or their respective designees, are members of the Oversight Committee. Each appointee serves staggered six-year terms and may include cancer survivors and family members of cancer patients. Page 4

Appropriations House Bill 1, Eightieth Legislature, 2007, provided $6.6 million in General Revenue Related Funds for the 2008-09 biennium for the Cancer Council, contingent on the passage of a constitutional amendment be renamed the Cancer Prevention and Research Institute of Texas; and House Bill 4586, Eighty-first Legislature, 2009, appropriated $0.9 million out of General Revenue for operations of the Cancer Prevention and Research Institute for fiscal years 2009, 2010 and 2011. Page 5

Appropriations and Expenditures 2010-11 Biennium Senate Bill 1, 81 st Legislature, 2009, appropriated $450 million in General Obligation Bond Proceeds to CPRIT for the 2010-11 biennium. Award Cancer Research Grants Award Cancer Prevention Grants* Direct and Indirect Administration Appropriated $389,180,850 $43,492,650 $15,493,500 Expended $386,756,521 $43,550,251 $18,116,960 Amount Over/(Under) ($2,424,329) $57,601 $2,623,460 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, of the 2010-11 General Appropriations Act, provides an agency to transfer up to 12.5 percent from one Item of Appropriation to another Item of Appropriation. *Not included d is $42,000 out of General Revenue Dedicated d - Cancer Prevention and Research Fund No. 5136 for prevention grants. Page 6

Appropriations and Expenditures 2012-13 Biennium House Bill 1, 82 nd Legislature, 2011, appropriated $600 million in General Obligation Bond Proceeds to CPRIT for the 2012-13 Biennium. Award Cancer Research Grants Award Cancer Prevention Grants* Grant Review and Award Operations** Indirect Administration Appropriated $516,382,196 $58,037,134 $12,888,718 $5,816,844 Expended/ d/ Budgeted $504,388,007 $58,038,340 $24,217,153 $7,507,770 Amount Over/(Under) ($11,994,189) $1,206 $11,328,435 $1,690,926 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, 2012-13 General Appropriations Act, allows agencies to transfer up to 20 percent from one Item of Appropriation into another Item of Appropriation. *Not included is $24,000 out of General Revenue Dedicated - Cancer Prevention and Research Fund No. 5136 for prevention grants. **Not included is $40,000 out of Appropriated Receipts for fees paid by commercialization grant applicants for additional costs associated with the commercialization review Page 7

Appropriations and Expenditures Total for 2010-11 11 and 2012-13 13 Biennia Award Cancer Research Grants Award Cancer Prevention Grants* Direct and Indirect Administration** Appropriated $905,563,046 563 046 $101,529,784 $34,199,062 Expended $891,144,528 $101,588,591 $49,841,883 Amount Over/(Under) ($14,418,518) $58,807 $15,642,821 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, of the 2010-11 General Appropriations Act, provides an agency to transfer up to 12.5 percent from one Item of Appropriation to another Item of Appropriation and Article IX, Section 14.01 Transfer Authority, 2012-13 General Appropriations Act, allows agencies to transfer up to 20 percent from one Item of Appropriation into another Item of Appropriation. *Not included is $62,000 out of General Revenue Dedicated - Cancer Prevention and Research Fund No. 5136 for prevention grants. **Not included is $40,000 out of Appropriated Receipts for fees paid by commercialization grant applicants for additional costs associated with the commercialization review Page 8

CPRIT s Expenditures (In Millions) 2010-11 Expended 2012-13 Estimated/Budgeted $43.5 $18.1 $58.0 $31.7 $386.0 $504.4 Cancer Research Grants Cancer Prevention Grants FTEs: 20.5 Grant Review and Indirect Administration Cancer Research Grants Cancer Prevention Grants FTEs: 24.0 Grant Review and Indirect Administration Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Page 9

CPRIT Grant Programs CPRIT has awarded approximately $840.8 million in grant awards, and expects to award an additional $151.9 million through the end of fiscal year 2013, in 3 categories: Research - grants for basic science to translational research and clinical applications. These grants range from short-term projects to multi-year research programs at laboratories and research facilities throughout the state; Prevention- grants that target projects and new partnerships, that increase the availability of screening services provided and detection of cancer, to increase survival rates; and Commercialization - grants focus on the commercialization of cancer detection, drugs and devices that demonstrate significant potential. Page 10

Total CPRIT Grant Awards By Type As of December 5, 2012 Commercialization $95.9 million 11.4% Prevention $85.9 million 10.2% Research $659.0 million 78.4% Source: Cancer Prevention and Research Institute of Texas Total Grant Awards $840.8 million Total General Obligation Bond Proceeds Appropriated for Grants $1,007.1 million Page 11

Appropriations of Bond Proceeds and Bond Issuances 2010 2011* 2010-11 Biennial Total Appropriated $225,000,000 $225,000,000 $450,000,000 Issued 225,000,000 $62,575,000 $287,575,000** *House Bill 2251, 82 nd Legislature, 2011, removed the escrow requirement and allows the Texas Public Finance Authority to issue the CPRIT bonds as needed for expenditure. 2012 2013 (thru December 2012) 2012-13 Biennial Total Appropriated $300,000,000 $300,000,000 $600,000,000 Issued 75,700,000 $9,600,000 $85,300,000** Source: Legislative Budget Board and Texas Public Finance Authority **As of December 14, 2012, approximately $677,125,000 in Bond Proceeds appropriated to CPRIT during the 2010-11 and 2012-13 biennia remain unissued. Page 12