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SPONSORSHIP PROSPECTUS Welcome message from the Meeting Chairmen An unforgettable Neurosurgical Week in Naples! We have the great honour and pleasure to inform you that Naples will be a venue for a special week of the Neurological Surgery in June 2018, with the 2 nd Congress of Mediterranean Association of Neurological Surgeons (MANS) on 19 and 20 and the International Conference on Recent Advance on Neurotraumatology (ICRAN) from 20 to 22 June, which will be held in the same venue, the Congress Center of the Hotel Royal Continental, located in the spectacular and unique seafront of the world, the Gulf of Naples. Naples Tradition, Culture and History will fascinate and enchant you just like all its visitors since the last centuries. Sunny, lively and simply memorable. Naples is a perfect venue to host these special scientific events, which will bring surgeons from all over the world together, personally and professionally, under a unique spirit. Don t miss this tremendous opportunity to have your organization recognized by a global audience! We invite you to sponsor these special events. Have your company brand seen by hundreds of delegates, drive awareness of your products and services, network with industry professionals from around the world and foster relationships with colleagues from every sector of our industry including Science, Academia, and Business in an effort to drive overall industry collaboration. This is your opportunity to showcase your organization, your products and your capabilities on an international stage! This document outlines the sponsorship opportunities available for both MANS and ICRAN Congress. The benefits of each level of opportunity are detailed. However, we can work with organizations to tailor or customize in an effort to best support your marketing goals and budget for both of them or just one of two. Of course special opportunities will be offered to companies who support both the events! Corrado Iaccarino and Paolo Cappabianca ICRAN 2018 Conference Chairmen Francesco Tomasello MANS 2018 Congress President

MANS CONGRESS PRESENTATION As Honorary President of World Federation of Neurosurgery (WFNS), I have the pleasure to announce the organization of the 2 nd Congress of the Mediterranean Association of Neurological Surgeons (MANS), to be held June 19-20, 2018 at the Hotel Royal Continental in Naples (Italy). The first congress was held in Algeria in 2016, under the Presidency of Prof. Mohamed Djennas, and after the big success of the first edition, we are enthusiast to propose the organization of the second congress in Italy. The MANS Congress is intended as a big opportunity to let Neurosurgeons coming from the main Mediterranean European, North African and Middle Eastern countries meet together. We are confident that the Congress will be attended by almost 250 participants coming from Southern Europe, North-Africa and Middle East. The scientific program is going to be defined according to the following main topics: Spine, Pediatrics, Vascular, Functional, Skull Base, Radiosurgery, Women in neurosurgery. We are trying to arrange a Simulation Course Session, open to all participants, to stimulate a more interactive participation. We are providing grants to encourage the attendance of young neurosurgeons. We are finalizing the list of invited speakers that we will send you as soon as possible. In the meantime, we are attaching a preliminary list of invited speakers. The Congress will be organized under the auspices of WFNS (World Federation of Neurosurgical Societies), CAANS, (Continental Association of African Neurosurgical Societies), SINch (Italian Society of Neurosurgery), EANS (European Association of Neurosurgical Societies), SeENS (South Eastern Europe Neurosurgical Society). Even more interesting is the opportunity to participate simultaneously at two international events, MANS and ICRAN in order to join a whole international neurosurgical week in Naples from 19 to 22 June, 2018. Several sponsorships opportunities are offered to company willing to support us for this event. Don t miss the opportunity to attend MANS 2018 Congress in Naples to get in touch with leaders and outstanding neurosurgeons coming from Mediterranean countries to extend your business opportunities. Prof. Francesco Tomasello ICRAN CONGRESS PRESENTATION ICRAN (International Conference on Recent Advances on Neurotraumatology) will be held on June 20-22, 2018 in Naples (Italy). The congress venue is the Royal Continental Hotel. ICRAN is the congress of the Neurotraumatology Section of the WFNS chaired by prof. Franco Servadei who is Honorary President of ICRAN 2018 as well. The Congress will be chaired by myself as secretary of the Neurotrauma Section of the Italian Society of Neurosurgery and member of the Neurotraumatology Committee of the World Federation of Neurosurgical Societies (WFNS) and by Prof. Paolo Cappabianca, Secretary of the Italian Society of Neurosurgery. A participation of approximately 350 (hopefully more) European, African, Middle Eastern, Asian and South and North American partners, with particular regard to emerging countries, is expected. The Congress will be organized under the auspices of WFNS (World Federation of Neurosurgery), SINCH (Italian Association of Neurosurgery), EANS (European Association of Neurosurgery) and AO Neuro. The ICRAN program is under construction, and will be available soon on the website also under construction. Main topics will be about traumatic brain injury, neurointensivist management of cranial trauma, pediatric trauma, hemostasis management and various sessions for spine trauma surgery. The latter are organized together with Italian and European AO Spine exponents, Prof. Ducati and Prof. Barbagallo respectively. This year my project within ICRAN is to complete a consensus conference on cranioplasty, bringing together various authors of cranioplasty to try to produce some expert recommendation to publish. There is a first session with oral communication organization about the various types of materials, therapeutic strategies, and then 10/15 experts for each 5 different meeting rooms (about 50 peoples) will discuss about the various aspects of controversy. The program will be enriched with some pre-event Courses (June 18 and 19, 2018) will be held with 4 cadaver labs at the Center of Biotechnology at Cardarelli Hospital: - Course for Decompression Craniectomy - Global Neuro Course - Course on the cervical spine with anterior and posterior approaches The internationality of the event allows us to organize a cad lab with different types of instruments from different companies, unless there is a major interest from a company to monopolize the course. Numerous seminar lunch will take place during the congress program. These can be sponsored by a company in order attract the attention of participants on a particular topic/project of their interest through a prestigious speaker/opinion leader. No congress lunch will be organized in overlap with the sponsored seminar lunch. Even more interesting is the opportunity to participate simultaneously at two international events, ICRAN and MANS in order to join a whole international neurosurgical week in Naples from 19 to 22 June, 2018. Don t miss the opportunity to attend ICRAN to get in touch with Researchers and Surgeons coming from emerging countries to extend your business opportunities. Corrado Iaccarino, MD

SPONSORSHIP OPPORTUNITIES The prices are for single event. Special opportunities will be offered to companies who support both the events! Why you should participate as a Sponsor and/or Exhibitor? Increase your brand s strength and image in the marketplace Gain differentiation from your competitors Target your message and marketing Increase access to national and international markets EXHIBIT OPPORTUNITIES The exhibition is a vital part of the MANS & ICRAN Congresses. Every effort will be made to ensure that all exhibitors receive prime exposure and direct marketing opportunities with key players and decision makers in the field. EXHIBIT OPTIONS Small Booth (4 sq.m) 2.500,00 Medium Booth (6 sq.m) 4.000,00 Large Booth (12 sq.m) 8.000,00 The exhibition area is located in the main hall, close to the Auditorium and will house coffee breaks points. The cost includes the row space and electricity supply. Please note that the large booth is reserved only to platinum sponsor. Assignment of the space Space will be assigned on a first come first served basis. Anyway companies attending both ICRAN and MANS will choose their space first. If the space requested is not available, it is the practice of us to contact each company to discuss alternative space availabilities. We reserve the right to relocate or reassign booths at any time for the overall benefit of the congress. Rental of additional items A list of additional items to be rented to complete the set up of the stands can be requested to the Organizing Secretariat MCM srl.

EDUCATIONAL SPONSORSHIP 1- MANS SIMULATION COURSE: 5.000,00 2- MANS LECTURE/ TECHNICAL PRESENTATION: 2.500,00 The Sponsor will have the opportunity to hold a presentation of 10 minutes by an expert of your company during the following session in the main scientific program of the congress: NOVEL TECHNOLOGIES AND DEVICES IN NEUROSURGERY: Interactive Debate Companies-Experts, that is scheduled on June 20. The Companies, which will decide to participate at this Session, will illustrate the features and applications of their flagship product. In an interactive discussion Q A, the experts will emphasize their experience, their needs of product advancement and, eventually, their viewpoints in order to make the application or the procedure more effective. 1-ICRAN CADAVER LABS: 8.000,00 which will be held on June 18 or 19, 2018 at the Center of Biotechnology at Cardarelli Hospital. CERVICAL SPINE: ANTERIOR AND POSTERIOR APPROACHES CAD LAB (June 18) DECOMPRESSIVE CRANIECTOMY & CRANIAL RECONSTRUCTION CAD LAB (June 19) 2-ICRAN PRE-EVENT COURSE: 5.000,00 SONOGRAPHY IN NEUROINTESIVE CARE (June 19 at the Congress Center) The following is included in the cost: - Meeting room rental, standard equipment and operating room (cadaver lab); inclusion of course program on the web site (prior to the congress), and in the final program. - Possibility of sending an invitation email trough the congress organizer to target specialists who have signed up for the congress. - Enhanced company description on the official ICRAN 2018 web site and permission to set up roll up banners (provided by the sponsor) in the meeting room SEMINAR LUNCH: 5.000,00 The Sponsor will have the opportunity to demonstrate the company s scientific research to a targeted and selected audience during a Seminar of 60 minutes. The following is included in the costs: Room (limited to a maximum number of 80 people) equipped with a standard room set up and standard audio/visual equipment. Any changes or additions to this are at the cost of the sponsor. All food and beverage ordered will be at the sponsors'own expense Invitation email through the Congress Organizer Promotion of the Seminar on website and final program Promotion of your Seminar with your own roll up The seminar program needs to be approved by the Scientific Committee In the cost of the above mentioned sponsorship are not included travel and hotel accommodation costs of your invited speaker, but your logo will be acknowledged on the congress web site and on the scientific programme. HOSPITALITY SUITE/INNOVATION ROOM: 4.000,00 The Sponsor will have the possibility to show a selected audience your new products and devices in a private room for the duration of the congress. The hospitality suite will be included on directional signage of the congress Invitation flyer in the congress bag EDUCATIONAL GRANTS: 800,00 per participant per event The Congress wants to help increase capacity in lower-income countries by supporting attendance and accommodation (2 nights) of their promising scientists and doctors who otherwise could not afford to travel. By contributing to the Educational Grants, you will help these delegates attend the Congress (MANS or ICRAN) and return with knowledge and contacts that will make a difference in their home countries. As a Contributor to the Educational Grant, you will: be verbally acknowledged at the Opening Ceremony and be acknowledged as a contributor with your logo in the onsite pocket program and signage.

PRINTED ADVERTISEMENTS 1-PROGRAM ADVERTISEMENT: 1.000,00 Logo and name of the Sponsor will be printed on the final programme. 2-ONSITE PROGRAM ADVERTISEMENT Inside page 1.000,00 Double central pages 2.500,00 Inside back cover page 2.000,00 Outside back cover page 3.000,00 3-CONGRESS SIGNAGE: 2.000,00 Logo and name of the company will be printed on all congress signage. Sponsor will be responsible for providing all advertisement and other artwork in print-ready format, per the specifications communicated by the Congress Secretariat. 4-CONGRESS BAGS: supply + 1.000,00 (exclusive sponsorship) The official event bag gives your brand maximum exposure in the exhibition halls and congress rooms and long after the event. Supply branded bags that will be distributed to all registered participants. 5-BLOCK NOTES AND PENS: supply + 1.000,00 (exclusive sponsorship) Supply of block notes and pens that will be distributed to all registered participants. 6-CONGRESS LANYARDS: supply + 2.000,00 (exclusive sponsorship) Lanyards will be provided by the company. All the participants will wear them all over the Congress. 7-FLYERS: 2.000,00 The Sponsor will have the possibility to distribute flyers in the congress bags to all participants. DIGITAL ADVERTISEMENT WEB SITE ADVERTISEMENT: 1.000,00 Logo and name of the Sponsor will be displayed on the web site of the Congress with a link to the company s web site. BANNER AD ON CONGRESS WEB SITE: 4.000,00 NEWSLETTER BANNER AD: 2.000,00 Top banner displayed on the newsletter that will be sent out to the Congress database Hyperlink to individual website ON-SITE MOBILE APP: 6.000,00 (exclusive sponsorship) Delegates will be extended free access to the Congress onsite mobile application, available for most ios and Android mobile devices. The onsite mobile app will include the full Congress program schedule, exhibit floor plan, company descriptions, general venue and local city information. Your Exclusive Sponsorship includes: Featuring your custom graphic/banner on the access page of the mobile app An opportunity for two (2) push notifications sent to all delegates during the Congress Logo acknowledgement on the website, Congress pocket program RE-CHARGE STATION: 5.000,00 The onsite Re-Charge station will allow attendees to power up their mobile devices for free for the entire duration of the Congress. Your Sponsorship includes: Branding of the Re-Charge station with your company logo The opportunity to place your promotional material by your sponsored Re-Charge station Recognition with your logo on the website, Congress pocket program.

COMMERCIAL VIDEO: 5.000,00 A promotional video of your company will be displayed on 4 monitors located in the exhibition area. SPEAKER READY ROOM: 2.500,00 Your logo will be displayed on the P.C. in the speaker ready room. COMPANY SLIDE: 2.000,00 Projection of your company slide on the screen of the main room during the session breaks. NETWORKING EVENTS SUPPORTING COFFEE BREAKS : 3.0000,00 (exclusive sponsorship) Associate your brand with an enjoyable networking occasion for all participants. Your logo will be displayed on the main room before the coffee breaks start. Your banners displayed in the same area (to be supplied by the sponsor). SUPPORTING LUNCH: 5.000,00 (exclusive sponsorship) Associate your brand with an enjoyable networking occasion for all participants. Your logo will be displayed on the main room before the lunches start. Your banners displayed in the same area (to be supplied by the sponsor). SUPPORTING NETWORKING DINNER: 10.000,00 (exclusive sponsorship) You will be given the opportunity to support the organization of the Networking dinner. Your brand will be printed on tickets for the social dinner and on the menu cards. Your banners displayed at the event (to be supplied by the sponsor). SUPPORTING FACULTY DINNER: 2.500,00 You will be given the opportunity to support the organization of the Faculty Dinner. Your brand will be printed on tickets for the faculty dinner and on the menu cards. Your banners displayed at the event (to be supplied by the sponsor). HOTEL RESERVATION For hotel reservation the Organizing Secretariat is at your disposal to make a special offer in the congress venue, for you and your guests, by March 1, 2018.

SPONSOR PACKAGES Acknowledgement on the Congress pocket program and website (with logo, web link and 150-word write-up) Banner advertising on the website PLATINUM GOLD SILVER BRONZE 15.000,00 10.000,00 7.000,00 4.000,00 0 0 0 Educational grants 8 6 4 2 Exhibit Spaces (sq.m) 12 6 6 4 Exhibitors pass 6 4 4 2 Delegate Bag Insert (supplied by Sponsor) 2 2 1 1 Full Page Advertisement in the Onsite Congress Pocket Program Inside back cover page Interior page 0 0 Networking dinner ticket 4 2 0 0 Company slide All prices are without Italian VAT. Please note NON EU Company are free of Italian VAT. We are more than open to discuss any other possibilities and to agree a tailor made platinum, gold or silver sponsorship. Please contact our dedicated Sponsorship and Exhibit Sales Manager to discuss the various items and pricing options: ORGANISING SECRETARIAT Rione Sirignano, 5-80121 Napoli (Italy) ph. +39 0817611085 - fax + 39 081664372 e.mail: panico@mcmcongressi.it www.mans2018.it - www.icran2018.it

SPECIAL OPPORTUNITIES MANS & ICRAN For those sponsoring both ICRAN and MANS Congresses special discounted rates will be available EXHIBIT OPTIONS MANS + ICRAN Small Booth (4 sq.m) 4.000,00 Medium Booth (6 sq.m) 7.000,00 Large Booth (12 sq.m) 12.000,00 SPONSOR PACKAGES Acknowledgement on the Congress pocket program and website (with logo, web link and 150-word write-up) Banner advertising on the website PLATINUM GOLD SILVER BRONZE 25.000,00 15.000,00 10.000,00 6.000,00 0 0 0 Educational grants 8 6 4 2 Exhibit Spaces (sq.m) 12 6 6 4 Exhibitors pass 6 4 4 2 Delegate Bag Insert (supplied by sponsor) 2 2 1 1 Full Page Advertisement in the Onsite Congress Pocket Program Inside back cover page Interior page 0 0 Networking dinner ticket 4 2 0 0 Company slide All prices are without Italian VAT. Please note NON EU Company are free of Italian VAT. In case of participation to both congresses, special discounts on single items can be discussed.