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Page 1 CUBAN INDUSTRIAL PROPERTY OFFICE (OFICINA CUBANA DE LA PROPIEDAD INDUSTRIAL) AS DESIGNATED (OR ELECTED) OFFICE CONTENTS THE ENTRY INTO THE NATIONAL PHASE SUMMARY THE PROCEDURE IN THE NATIONAL PHASE ANNEXES Fees... Power of attorney... Deed of assignment... Annex CU.I Annex CU.II Annex CU.III List of abbreviations: Office: Cuban Industrial Property Office DL290/2011: Decree-Law No. 290, on Inventions and Industrial Designs and Models (of 20 November 2011)

SUMMARY Page 3 Designated (or elected) Office CU SUMMARY CU CUBAN INDUSTRIAL PROPERTY OFFICE CU Summary of requirements for entry into the national phase Time limits applicable for entry into the national phase: Translation of international application required into: 1 Required contents of the translation for entry into the national phase: 1 Is a copy of the international application required? Under PCT Article 22(1): 30 months from the priority date Under PCT Article 39(1)(a): 30 months from the priority date Spanish Under PCT Article 22: Description, claims (if amended, both as originally filed and as amended, together with any statement under PCT Article 19), any text matter of drawings, abstract Under PCT Article 39(1): Description, claims, any text matter of drawings, abstract (if any of those parts has been amended, both as originally filed and as amended by the annexes to the international preliminary examination report) No National fee: Currency: Cuban convertible peso (CUC) For patent: Filing fee (including publication fee and the annual fee for the 1 st and the 2 nd years): 2 CUC 460 For utility model: Filing fee (including publication fee and the annual fee for the 1 st and the 2 nd years): 2 CUC 350 Exemptions, reductions or refunds of the national fee: Fees are reduced by CUC 50 where applications are filed both on paper and in electronic form [Continued on next page] 1 If not already furnished within the time limit applicable under PCT Article 22 or 39(1), the Office will invite the applicant to comply with the requirement within a time limit of 60 days. If the translation of the amended application is not furnished, the Office will proceed on the basis of the translation of the application as originally filed. If the translation of the application as originally filed is not furnished, the application will be considered abandoned. 2 The Office may also require payment of the third annual fee at the time of filing, depending on the date of entry into the national phase.

Page 4 SUMMARY CU Designated (or elected) Office CUBAN INDUSTRIAL PROPERTY OFFICE [Continued] SUMMARY CU Special requirements of the Office (PCT Rule 51bis): 3 Who can act as agent? Does the Office accept requests for restoration of the right of priority (PCT Rule 49ter.2)? Instrument of assignment or transfer where the applicant is not the inventor 4 Instrument of assignment of the priority right where the applicants are not identical 4 Appointment of an agent if the applicant does not have a domicile or a real or effective industrial or commercial establishment in Cuba Evidence concerning non-prejudicial disclosures or exceptions to lack of novelty, such as disclosures resulting from abuse and disclosures by the applicant in official or officially recognized exhibitions 5 Verification and translation of the international application to be furnished in two copies Furnishing, where applicable, of a nucleotide and/or amino acid sequence listing in electronic form and paper and a declaration that the sequences are identical in both formats 6 Any person authorized to practice before the Office. The names and professional addresses of the persons who can act as agents are published in the Official Gazette [Boletín Oficial de la Oficina]. No 3 If not already complied with within the time limit applicable under PCT Article 22 or 39(1), the Office will invite the applicant to comply with the requirement within a time limit of 60 days subject to the payment of the applicable fee. Before the expiration of that period, the applicant may request another extension of 30 days subject to the payment of the applicable fee. 4 This requirement may be satisfied if the corresponding declaration has been made in accordance with PCT Rule 4.17. 5 Documents relative to official or officially recognized exhibitions must be submitted to the Office within a non-extendable period of three months from the date of entry into the national phase. 6 The documents must be submitted to the Office within 16 months from the date of filing of the application or, if applicable, from the date of the priority claim.

Page 5 CU THE PROCEDURE IN THE NATIONAL PHASE CU.01 TRANSLATION (CORRECTION). Errors in the translation of the international application can be corrected with reference to the text of the international application as filed (see National Phase, paragraphs 6.002 and 6.003). CU.02 FEES (MANNER OF PAYMENT). The manner of payment of the fees indicated in the Summary and in this Chapter is outlined in Annex CU.I. DL290/2011 15 CU.03 POWER OF ATTORNEY. An agent authorized to practice before the Office must be appointed by filing a power of attorney if the applicant does not have a domicile or a real and effective industrial and commercial establishment in Cuba. A model is given in Annex CU.II. DL290/2011 8 CU.04 ASSIGNMENT DEED. For details, see the model in Annex CU.III. If the applicant has obtained the right to file the international application through one or more other persons and not directly from the inventor, an assignment deed linking the inventor and the applicant must be presented. This requirement may be satisfied if the corresponding declaration has been made in accordance with PCT Rule 4.17. CU.05 Where the priority of an earlier application is claimed and the applicant is not the same as the applicant of the original application, a copy of the instrument granting the right to claim the priority of the earlier application to the current applicant must be submitted. This requirement may be satisfied if the corresponding declaration has been made in accordance with PCT Rule 4.17. DL290/2011 20.2 CU.06 DIVISIONAL APPLICATIONS. Where an application is divided, either at the request of the applicant or at the request of the Office, it will benefit from the same filing date and any applicable priority date as the international application which entered the national phase. The amount of the fee for a divisional application is indicated in Annex CU.I. DL290/2011 42 43 CU.07 ANNUAL FEES. Annual fees are payable from the international filing date and must be paid within 30 months from the priority date, regardless of whether or not preliminary examination has been carried out. Annual fees must be paid before the beginning of the year of validity. A period of grace of six months will be allowed for the payment of an expired annual fee, but the prescribed amount thereof will then be doubled. For the amount of these fees, see Annex CU.I. DL290/2011 131-134 CU.08 AMENDMENT OF THE APPLICATION; TIME LIMITS. The applicant may, before grant, request rectification of errors of form. A request for rectification of errors of substance can only be made by the applicant before publication, provided that such rectification does not go beyond the content of the application as originally filed. Any holder of a patent or utility model may request the inclusion of any amendment to his title of protection provided the documents that legally justify it are furnished. The amount of the fee payable for such amendment is indicated in Annex CU.I. DL290/2011 32 36 PCT Art. 25 PCT Rule 51 CU.09 EXCUSE OF DELAYS IN MEETINGS TIME LIMITS. Reference is made to paragraphs 6.022 to 6.027 of the National Phase. Where an official notice is not complied with within 60 days the application will be considered abandoned unless the applicant requests in writing an extension of 30 days and pays the corresponding fee. The amount of the extension fee is indicated in Annex CU.I. CU.10 REVIEW UNDER ARTICLE 25 OF THE PCT. The applicable procedure is outlined in paragraphs 6.018 to 6.021 of the National Phase.

Page 6 DL290/2011 39-41 CU.11 APPEALS. After substantive examination, a decision is issued by the Chief of the Technical Department, granting, granting in part or denying the application. In case of nonconformity, applicants may file an appeal with the Director of the Office, within 30 days from the date of the notification of said decision, upon payment of the corresponding fee. The amount of the appeal fee is indicated in Annex CU.I. DL290/2011 119 Applicants may file an appeal before the Provincial Tribunal of the City of Havana against the decision of the Director of the Office within 30 days from the date of the notification of said decision. CU.12 UTILITY MODEL. Subject to paragraph CU.14, if the applicant wishes to obtain a utility model instead of a patent in Cuba, on the basis of an international application, the applicant, when performing the acts referred to in Article 22 or 39, shall so indicate to the Office. The fees relating to utility models are indicated in Annex CU.I. DL290/2011 123 124 CU.13 REINSTATEMENT OF RIGHTS. Reinstatement of rights may be requested where the applicant failed to observe a time limit set by the Office in spite of due care, which is prejudicial to his rights. A request for reinstatement must be presented in writing within 60 days from the removal of the cause of the failure to observe the time limit or 12 months from the date of expiration of the applicable time limit. The omitted action must be completed within the applicable time limit, the request must state the facts which justify the reinstatement and set out the facts on which it relies, and the fee for reinstatement of rights (see Annex CU.I) must be paid. DL290/2011 83 CU.14 CONVERSION. During the processing of the international application, the applicant has the right to convert his application for a patent into an application for a utility model or vice versa within 12 months after entering the national phase, upon payment of the prescribed fee. The amount of the fee for conversion is indicated in Annex CU.I.

Annex CU.I, page 1 FEES (Currency: Cuban convertible peso) Patents Filing fee (including publication fee and the annual fee for the 1 st and the 2 nd years) 1... 460 2 Claim fee: for each independent claim in excess of one... 80 for each multiple dependent claim... 100 for each group up to ten dependent claims... 80 Fee for each page in excess of 30... 5 Fee for amendment or modification... 100 Fee for grant... 200 Fee for claiming priority, per priority... 50 Fee to respond to an invitation from the Office... 85 Fee for extension of time to respond to an invitation from the Office... 70 Fee for conversion... 150 Fee for appeal.... 200 Fee for reinstatement... 300 Fee for submission of divisional application 3... 350 Annual fees: for the 3 rd year... 200 for the 4 th year... 250 for the 5 th year... 300 for the 6 th year... 350 for the 7 th year... 400 for the 8 th year... 450 for the 9 th year... 500 for the 10 th year... 550 for the 11 th year... 600 for the 12 th year... 650 for the 13 th year... 700 for the 14 th year... 750 for the 15 th year... 800 for the 16 th year... 900 for the 17 th year... 1,000 for the 18 th year... 1,100 for the 19 th year... 1,200 for the 20 th year... 1,300 late payment fee in period of grace of six months... double of the corresponding fee 1 The Office may also require payment of the third annual fee at the time of filing, depending on the date of entry into the national phase. 2 This fee is reduced by CUC 50 where the application is filed both on paper and in electronic form. 3 The first and second annuities are not included. A surcharge of CUC 40 is added where more than one invention or group of inventions is claimed in the same application.

Annex CU.I, page 2 Utility models Filing fee (including publication fee and the annual fee for the 1 st and the 2 nd years) 4... 350 5 Fee for grant... 150 Fee for submission of divisional application 6... 350 for each group of up to five claims... 80 Annual fees: for the 3 rd year... 150 for the 4 th year... 200 for the 5 th year... 250 for the 6 th year... 300 for the 7 th year... 350 for the 8 th year... 400 for the 9 th year... 450 for the 10 th year... 500 How can payment of fees be effected? The payment of fees must be effected in Cuban convertible pesos. All payments must indicate the application number (national, if already known; international, if the national application number is not yet known), the name of the applicant and the category of fee being paid. All fees must be paid to the Office, either by check or in cash. 4 See footnote 1. 5 See footnote 2. 6 See footnote 3.

Annex CU.II DOCUMENTO DE REPRESENTACIÓN/ POWER OF ATTORNEY/ POUVOIR Yo/Nosotros/ I/We/ Je/ Nous 1 : Nombro/ nombramos/ do hereby appoint/ nomme/nommons 2 : Para encargarse en mi/ nuestro nombre de los trámites para presentar la solicitud relativa a la invención titulada 3 / To undertake on my/our behalf the procedures for filing an application in relation to the invention entitled 4 /Pour accomplir en mon/notre nom les formalités de depòt d'une demande relative à l'invention intitulée 5 : En la Oficina Cubana de la Propiedad Industrial Before the Cuban Industrial Property Office Auprés de l'office Cubain de la Propriété Industrielle De conformidad con la legislación cubana sobre invenciones/ according to the cuban legislation on inventions/ conformément à la législation cubaine sur les inventions. Lugar/ Place/Lieu Fecha/Date Firma(s)/Signature(s) NO SE REQUIERE LEGALIZACIÓN/ NO LEGALIZATION REQUIRED/ AUCUNE LÉGALISATION REQUISE 1 Indicar de manera completa (a) los nombres y apellidos y (b) la dirección de la persona o de la empresa que ha nombrado al mandatario/ Insert in full (a) the name and (b) address of the individual or corporation appointing the attorney/ Indiquer le nom complet (a) et l adresse complète (b) de la personne ou de la societé qui nomme le mandataire. 2 Nombre del mandatario/ Name of attorney/ Nom du mandataire. 3 Título de la invención / Title of the invention/ Titre de l invention. 4 IDEM Nota al Pie 20. 5 IDEM Nota al Pie 20.

Annex CU.III ACTA DE CESIÓN/ DEED OF ASSIGNEMENT/ ACTE DE CESSION Yo/Nosotros/ el que suscribe/ los que suscriben: It is hereby declared that I / we the undersigned: Je/ Nous soussigné(s): Declaro/ declaramos por la presente Acta haber cedido mi /nuestro derecho de solicitar y obtener una patente de invención o un registro de modelo de utilidad en Cuba relativa a la invención intitulada: I / we declare by this Act have given my/ our right to request and obtain a patent for invention or utility model registration in Cuba on the invention entitled: Je déclare / Nous déclarons par la présente acte avoir cédé mon / notre droit de demander et d'obtenir un brevet d'invention ou d'un modèle d'utilité à Cuba sur l'invention intitulée: a/to/à: Lugar/ Place/Lieu Fecha/Date Firma(s)/Signature(s) NO SE REQUIERE LEGALIZACIÓN/ NO LEGALIZATION REQUIRED/ AUCUNE LÉGALISATION REQUISE