IN THE COURT OF CHANCERY OF THE STATE OF DELAWARE ) ) SCHEDULING ORDER. Pharmaceuticals Stockholders Litigation, Consol. C.A. No.

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EFiled: Oct 20 2015 11:35AM EDT Transaction ID 58039964 Case No. 10553-VCN IN THE COURT OF CHANCERY OF THE STATE OF DELAWARE IN RE NPS PHARMACEUTICALS STOCKHOLDERS LITIGATION ) ) CONSOLIDATED C.A. No. 10553-VCN SCHEDULING ORDER WHEREAS, the parties to the consolidated class action captioned In re NPS Pharmaceuticals Stockholders Litigation, Consol. C.A. No. 10553-VCN (the Action ), having applied pursuant to Court of Chancery Rule 23(e) for an order approving the proposed settlement of the Action in accordance with the Stipulation and Agreement of Compromise, Settlement, and Release entered into by the parties on October 1, 2015 (the Stipulation ), and for dismissal of the Action on the merits with prejudice upon the terms and conditions set forth in the Stipulation (the Settlement ); WHEREAS, the Stipulation contemplates final certification by this Court of a class action, solely for the purposes of settlement; and WHEREAS, the Court has read and considered the Stipulation and accompanying documents; and WHEREAS, all parties have consented to the entry of this Order; NOW, THEREFORE, IT IS HEREBY ORDERED this 20th day of October, 2016, that:

1. Except for terms defined herein, the Court adopts and incorporates the definitions in the Stipulation for purposes of this Order. 2. For settlement purposes only, the Action shall be maintained, pursuant to Court of Chancery Rules 23(a), 23(b)(1), and 23(b)(2), as a non-opt-out class consisting of any and all record holders and beneficial owners of common stock of NPS Pharmaceuticals, Inc. ( NPS ) (excluding the Defendants and their immediate family members, any entity in which any Defendant has a controlling interest, and any successors in interest thereto), their respective successors in interest, successors, predecessors in interest, predecessors, representatives, trustees, executors, administrators, heirs, assigns or transferees, immediate and remote, and any person or entity acting for or on behalf of, or claiming under, any of them, and each of them, together with their predecessors and successors and assigns, who owned or held shares of NPS common stock at any time between and including January 11, 2015 through and including February 21, 2015. 3. The Court has appointed the law firms Pomerantz LLP and WeissLaw LLP as Plaintiffs co-lead counsel ( Co-Lead Counsel ) to the Class. 4. A hearing (the Settlement Hearing ) shall be held on January 13, 2016, at 2:00 p.m., in the Kent County Courthouse, 414 Federal Street, Dover, Delaware 19901, to: a. determine whether the preliminary certifications herein should be made final; 2

b. determine whether the Settlement should be approved by the Court as fair, reasonable, adequate, and in the best interests of the Class; c. determine whether an Order and Final Judgment should be entered in the Action pursuant to the Stipulation; d. hear and determine any objections to the Settlement or to the application of Co-Lead Counsel in the Action for an award of attorneys fees and expenses; e. consider the application of Co-Lead Counsel for an award of attorneys fees and expenses; and f. rule on such other matters as the Court may deem appropriate. 5. The Court reserves the right to adjourn or reschedule the Settlement Hearing or any adjournment thereof, including the consideration of the application for attorneys fees, without further notice of any kind other than oral announcement at the Settlement Hearing or any adjournment thereof or written notice on the docket in the Action. 6. The Court reserves the right to approve the Settlement at or after the Settlement Hearing with such modification(s) as may be consented to by the parties to the Stipulation and without further notice to the Class. 7. At least 60 calendar days prior to the Settlement Hearing, NPS or its successor-in-interest shall cause a Notice of Pendency of Class Action, Proposed Class Action Determination, Proposed Settlement of Class Action, Settlement Hearing, and Right to Appear (the Notice ), substantially in the form annexed as Exhibit C to the Stipulation, to be mailed by United States mail, postage pre-paid, 3

to all reasonably identifiable members of the Class at their last known addresses set forth in the stock transfer records maintained by or on behalf of NPS. All record holders in the Class who were not also the beneficial owners of the shares of common stock of NPS held by them of record are requested to forward the Notice to such beneficial owners of those shares. NPS or its successor-in-interest shall use reasonable efforts to give notice to such beneficial owners by (i) making additional copies of the Notice available to any record holder who, prior to the Settlement Hearing, requests copies for distribution to beneficial owners, or (ii) mailing additional copies of the Notice to beneficial owners as reasonably requested by record holders who provide names and addresses for such beneficial holders. NPS or its successor-in-interest shall be responsible for and shall pay all costs and expenses incurred in providing such Notice to the members of the Class. 8. The Court approves, in form and substance, the Notice. The form, mailing, and distribution of the Notice is the best notice practicable and shall constitute due and sufficient notice of the Settlement Hearing to all persons entitled to receive such notice, and fully satisfies the requirements of due process, Court of Chancery Rule 23, and applicable law. 9. Counsel to NPS or its successor-in-interest shall, at least 10 business days prior to the date of the Settlement Hearing directed herein, file with the Court proof of mailing of the Notice. 4

10. All proceedings in the Action, other than such proceedings as may be necessary to carry out the terms and conditions of the Settlement, are hereby stayed and suspended until further order of this Court. Pending final determination of whether the Settlement should be approved, Plaintiffs, and all members of the Class, are barred and enjoined from commencing, prosecuting, instigating, or in any way participating in the commencement or prosecution of any action asserting any Released Claims, either directly, representatively, derivatively, or in any other capacity, against Defendants or any of the Released Persons. 11. Any member of the Class who objects to any aspect of the Settlement and/or the Order and Final Judgment to be entered in the Action, or who otherwise wishes to be heard, may appear in person or by his or her attorney at the Settlement Hearing and present evidence or argument that may be proper and relevant; provided, however, that, except for good cause shown, no person other than Co- Lead Counsel and counsel for the Defendants shall be heard and no papers, briefs, pleadings, or other documents submitted by any member of the Class shall be considered by the Court unless, not later than 10 business days prior to the Settlement Hearing directed herein, (i) a written notice of intention to appear; (ii) proof of membership in the Class; (iii) a detailed statement of the objections by the member of the Class to any matters before the Court; (iv) a statement advising the Court and the parties of any court proceeding in which said objector has made an 5

objection to a proposed class action settlement within the past three years, including case name, docket number, and court; and (v) the grounds therefor or the reasons why such member of the Class desires to appear and be heard, as well as all documents or writings such person desires the Court to consider, are filed by such person with the Court, and, on or before such filing, are served by hand or overnight mail on the following counsel of record: Gustavo F. Bruckner POMERANTZ LLP 600 Third Avenue New York, NY 10016 Co-Lead Counsel for Plaintiffs and the Class Richard A. Acocelli WEISSLAW LLP 1500 Broadway, 16 th Floor New York, NY 10036 Co-Lead Counsel for Plaintiffs and the Class Jennifer C. Voss SKADDEN, ARPS, SLATE, MEAGHER & FLOM LLP One Rodney Square P.O. Box 636 Wilmington, DE 19899-0636 Counsel to the NPS Defendants William M. Lafferty MORRIS NICHOLS, ARSHT & TUNNELL LLP 1201 North Market Street, 16 th Floor P.O. Box 1347 Wilmington, DE 19899-1347 Counsel to the Shire Defendants 6

12. Unless the Court otherwise directs, no member of the Class shall be entitled to object to the Settlement or to the Order and Final Judgment to be entered, or to the award of attorneys fees and expenses to Co-Lead Counsel, or otherwise to be heard, except by serving and filing written objections as prescribed in Paragraph 12. Any member of the Class who fails to object in the manner described above shall be deemed to have waived the right to object (including any right of appeal) and shall be forever barred from raising such objection in this or any other action or proceeding. 13. Plaintiffs shall file and serve their opening brief in support of the Settlement and their application for attorneys fees and expenses no later than 15 business days prior to the Settlement Hearing. Any objections to the application for attorneys fees and expenses shall be filed and served no later than 10 business days prior to the Settlement Hearing. If any objections to the Settlement are received or filed, Plaintiffs and/or Defendants may file and serve a response to those objections no later than 5 business days prior to the Settlement Hearing. 14. The Stipulation and any negotiations, statements, or proceedings in connection therewith, shall not be construed or deemed evidence of, a presumption of, concession of, or admission by, any of the Released Persons or any other person of any fault, liability, or wrongdoing as to any facts or claims alleged or asserted in the Action or otherwise, or that Plaintiffs, or Co-Lead Counsel, the Class, or any 7

present or former stockholders of NPS, or any other person, have suffered any damage attributable in any manner to any of the Released Persons. The Stipulation and any negotiations, statements, or proceedings in connection therewith, shall not be construed or deemed evidence of, a presumption of, concession of, or admission of lack of merit of any of Plaintiffs claims. The existence of the Stipulation, its contents, and any negotiations, statements, or proceedings in connection therewith, shall not be offered or admitted into evidence or referred to, interpreted, construed, invoked, or otherwise used by any person for any purpose in the Action or otherwise, except as may be necessary to enforce or obtain Court approval of the Settlement. Notwithstanding the foregoing, any of the parties may file the Stipulation, or any judgment or order of the Court related hereto, in any other action that may be brought against them, in order to support any and all defenses or counterclaims based on the entire controversy doctrine, res judicata, collateral estoppel, release, good-faith settlement, judgment bar or reduction, or any other theory of claim preclusion or issue preclusion, or similar defense or counterclaim. 15. If the Settlement is approved by the Court, following the Settlement Hearing, a Final Order and Judgment will be entered as described in the Stipulation. 16. If the Settlement, including any amendment made in accordance with the Stipulation, is not approved by the Court or shall not become effective for any 8

reason whatsoever, the Settlement (including any modification thereof made with the consent of the parties as provided for in the Stipulation), and preliminary certifications herein and any actions taken or to be taken in connection therewith (including this Scheduling Order and any judgment entered herein) shall be terminated and shall become void and of no further force and effect, except for NPS s obligation to pay for any expenses incurred in connection with the Notice and administration provided for by this Scheduling Order. In that event, neither the Stipulation, nor any provision contained in the Stipulation, nor any action undertaken pursuant thereto, nor the negotiation thereof by any party, shall be deemed an admission, concession, or received as evidence in this or any other action or proceeding. 17. The Court may, for good cause, extend any of the deadlines set forth in this Order without further notice to members of the Class. APPROVED AND SO ORDERED this 20th day October, 2015. /s/ John W. Noble Vice Chancellor 9