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Contents Welcome Letter... 3 Profile of Attendance... 4 Preliminary List of Topics... 4 International Scientific Committee... 5 General Information......6 Master Course Program... 8 Information for Sponsors and Exhibitors....9 Registration Information... 10 Sponsorship Opportunities... 11 Sponsorship Application Form and Contract... 19 Information for Exhibitors... 21 Exhibition Application Form and Contract... 24 2

Welcome letter from the EAP President Dear Colleagues, After careful preparation, and with a view to being different from other paediatric conferences, the EAP Congress and MasterCourse has attained a very special reputation. This, despite the ever-increasing number of conferences in Paediatrics. The conference will present a one-and-a-half-day workshop entitled MasterCourse in Paediatrics, which is based on most recent publications, promises to be an excellent event. The MasterCourse will focus on nutrition from birth to adolescent and will take place 19-20 September, 2019. The scientific chairmen, Prof. Berthold Koletzko and Prof. Jorge Amil Dias have prepared an excellent programme with renowned faculty members. The MasterCourse in Paediatrics will take place in relatively small break-out rooms with only limited seating capacity. I therefore recommend early registration. The scientific committee of the congress has set up an interesting programme for both senior and junior doctors which covers in depth important clinical subjects. Once again, we anticipate a significant scientific contribution from junior doctors and encourage them to submit abstracts. Accepted abstracts will be presented as posters or oral presentations with lead authors of these abstracts automatically eligible for sending an application for a travel grant.(see eligible criteria) Accepted abstracts will be published in the European Journal of Paediatrics and therefore, citable. I am looking forward to welcoming you to Porto in September which is one of the most beautiful periods of the year. There is no better time to combine knowledge with pleasure! Adamos Hadjipanayis, MD, PhD EAP President, 3

Target Audience The 2019 EAP Congress & MasterCourse are open for all paediatricians, nurses, trainees, students and scientists who specialise in paediatric filed Topics Congress Topics Adolescent Medicine Allergy & Immunology Critical / Emergency Care Endocrine & Diabetes Gastroenterology & Nutrition Genetic & Metabolic Hemato - Oncology Infectious Diseases Neonatology Nephrology Neurology Pediatric Tropical Medicine Pediatric Cardiology Primary Care Obesity Respiratory Rheumatology MasterCourse Topics Nutrition in Early Life Counselling Mothers with Breastfeeding Challenges Complementary Feeding: Impact on Allergy Risk Human Milk Substitutes: When to Use which Formula? Cow s Milk Protein Allergy and Food Intolerance Childhood Obesity: Assessment and Treatment Disease Associated Malnutrition Enteral Nutrition Therapy in Paediatrics Nutrition in Paediatric Inflammatory Bowel Disease Parenteral Nutrition in Infants and Children 4

Committees Scientific Committee of the EAP Congress Robert Ross Russel, UK Adamos Hadjipanayis, Cyprus Ana Neves, Portugal Arunas Valiulis, Lithuania Karoly Illy, The Netherlands Jernej Zavrsnik, Slovenia Ines Azevedo, Portugal Preliminary MasterCourse & Congress Timeline MasterCourse Nutrition Berthold Koletzko, Germany, MasterCourse Chair Jorge Amil Dias, Portugal, MasterCourse Co-Chair 5

General Information Venue Porto Palacio Hotel Congress Hotel Av. Boavista, 1269 Dates 19-22 September, 2019 Registration & Accommodation All participants must submit a completed registration form. Hotel accommodation at special conference rates is available to participants on the congress website. Language The official language of the Congress is English CME Accreditation An application for CME accreditation will be made to the European Accreditation Council for Continuing Medical Education (EACCME). The EACCME is an institution of the European Union of Medical Specialists (UEMS): www.uems.net. Further details will be available in due time Letter of Invitation Official letters of invitation designed to assist with obtaining an entry visa can be downloaded from the Congress website. Please note that such letters do not represent a commitment on the part of the Organizing Committee or Congress to provide any financial assistance. Visas Some participants may require a visa to travel to Portugal. Participants are requested to check with the Portugal consulate in their home country. It is the responsibility of the participants to obtain a visa as necessary. 6

Liability and Insurance The Congress organizers cannot accept liability for personal injuries sustained, or for loss or damage of property belonging to Congress participants (or their accompanying persons), either during, or as a result of the Congress. Delegates and their accompanying guests are strongly advised to purchase adequate travel insurance for the duration of their travel, the Congress and tours. Dress Code Informal for all occasions. Congress Secretariat Paragon Group 18 Avenue Louis Casai 1209 Geneva Switzerland Tel: +41 22 5330 948 (Ext. 204) Fax: +41 22 5802 953 Email: congress@eapaediatrics.eu 7

European Academy of Paediatrics - MasterCourse 2019 Paediatric Nutrition 19-20 September, Porto, Portugal Thursday,19.09.2019 07:30-08:30 Registration 08:30-08:45 Welcome and Introduction: Housekeeping Information Berthold Koletzko, Germany; Jorge Amil Dias, Portugal Master Course Breakout Groups 08:45-11:00 Case Studies 1 Case Studies 2 Case Studies 3 Case Studies 4 11:00-11:30 Coffee Break Master Course Plenary Lectures 11:30-12:15 Nutrition in Early Life: Why is it Important? Berthold Koletzko, Germany 12:15-13:00 Counselling Mothers with Breastfeeding Challenges TBD 13:00-13:45 Lunch Break Master Course Plenary Lectures 13:45-14:30 Complementary Feeding: Impact on Allergy Risk Antonio Guerra, Portugal 14:30-15:15 Human Milk Substitutes: When to use which Formula? TBD D 15:15-16:00 Cows Milk Protein Allergy and Food Intolerance Jorge Amil Dias, Portugal 16:00-16:30 Coffee Break 16.30-17:15 Childhood Obesity: Assessment and Treatment Carla Rego, Portugal 17:15-18:00 Disease Associated Malnutrition Sanja Kolaczek, Croatia Friday, 20.09.2019 07:30-08:30 Coffee Break Master Course Plenary Lectures 08:30-09:15 Enteral Nutrition Therapy in Paediatrics Sanja Kolaczek, Croatia 09:15-10:00 Nutrition in Paediatric Inflammatory Bowel Disease Eunice Trindade, Portugal 10:00-10:45 Parenteral Nutrition in Infants and Children TBD 10:45-11:15 Coffee Break 11:15-12:00 Nutritional Care of Preterm Infants Berthold Koletzko, Germany Master Course Breakout Groups 12:00-13:15 Case Studies 1 Case Studies 2 Case Studies 3 Case Studies 4 13:15-13:30 Conclusions 8

Information for Sponsors and Exhibitors Application for Sponsorship Application for Sponsorship can be made in writing with the enclosed booking form to: Paragon Group Mrs. Yael Ziv 18, Avenue Louis-Casai, 1209 Geneva, Switzerland Tel: +41 (0)22 533 0948 ; Fax: +41 (0)22 5802 953 (Ext. 208) Email: Yziv@paragong.com All company details, as filled in the form, will be used for advertisement. Once an application is made, a contract will be sent for completion. The contract should be signed and returned with a 50% deposit payment to the above Sponsorship/Exhibition office address. Alternatively, an invoice for the deposit can be requested on the booking form. Once this has been received, a confirmation of Sponsorship and an invoice will be sent to the Sponsor. Terms of Payment 50% due with signed contract 50% due by June 1, 2019 The total amount should be received before the opening date of the Congress. Payment Methods Option 1: Payment by credit card Option 2: Payment by bank transfer: Details will be provided in the invoice. Bank charges are the responsibility of the payer. Cancellation Policy Cancellations will be accepted in writing only. A cancellation notice received by June 1, 2019, will entitle a reimbursement of 50% of the sponsorship payment, under the condition that the allocated space will be rented to another exhibitor. No reimbursement will be possible after June 1, 2019. Terms and Conditions The terms and conditions of Sponsorship and Exhibition are included in this prospectus. Please note that a signature on the Exhibition contract indicates the acceptance of these terms and conditions. 9

Registration Information Please note that registration to the congress will open soon. Registration fees will be payable in Euros. Amex credit card holders will be charged in US Dollars. Fees for Congress participants include participation in all scientific sessions, printed material of the Congress, an invitation to the Welcome Reception, coffee breaks, and entrance to the Exhibition. Group Registration Policy The group registration policy is valid for groups with a minimum of 20 delegates. For further details, please contact the Congress and MasterCourse Registration Department. 20-29 pax- 10% discount 30-49 pax- 12% discount 50-100 pax- 15% discount 100-200 pax- 20% discount Hotel Information Companies interested in booking hotel accommodation are kindly requested to contact the Registration Department at Paragon Group. Registration Department Contact Details Paragon Group Ms. Pamela Levi Vaserman 18 Avenue Louis-Casai 1209 Geneva, Switzerland Tel: +41 (0)22 533 0948 Fax: +41 (0)22 580 2953 E-mail : Registration@eapcongress.com 10

Sponsorship Opportunities An exciting range of Sponsorship opportunities has been created to allow each company to showcase itself as best suits their needs and budget. Diamond Sponsorship - 50,000 Platinum Sponsorship - 40,000 Gold Sponsorship - 30,000 Silver Sponsorship - 15,000 Companies exhibiting will be acknowledged as exhibitors. See below the packages that we have created for Diamond, Platinum, Gold, Silver Sponsors. Feel free to speak with our industry manager about a tailor-made individual package for your organization. Anything is possible! 11

Diamond Sponsorship Package 50,000 Organization of a Satellite Symposium Sponsorship of a Satellite Symposium, for up to 90 minutes. The programme is subject to the approval of the Congress Scientific Committee (Satellites will be allocated on a first come, first served basis ). Includes: Hall rental, standard audio/visual equipment, display table Permission to use the phrase: "Official Satellite Symposium of EAP 2019." Symposium programme and abstracts will be included in the Final Programme (Subject to receipt by publishing deadline). Exhibition Space 18 sqm exhibition space. Diamond Priority space allocation. Additional space can be purchased upon request at a reduced cost of 300 per square meter. 10 exhibitor registrations. Advertisement Inclusion of sponsor's symposium invitation in the Congress bags (insert to be provided by sponsors.) Inclusion of one further insert for promotional purposes in the Congress bag (Insert of up to 8 A4 pages to be provided by sponsor). Acknowledgment of Sponsorship in the Congress book as "Diamond Sponsor" A color advertisement in the Final Programme/Book of Abstracts Sponsor's logo with hyperlink on Congress website. Inclusion of symposium programme on the Congress website. 12

Platinum Sponsorship Package 40,000 Organization of a Satellite Symposium Sponsorship of a Satellite Symposium, for up to 60 minutes. The programme is subject to the approval of the Congress Scientific Committee (Satellites will be allocated on a first come, first served basis ). Includes: Hall rental, standard audio/visual equipment, display table Permission to use the phrase: "Official Satellite Symposium of EAP 2019. "Symposium programme and abstracts will be included in the Final Programme (Subject to receipt by publishing deadline). Exhibition Space 18 sqm exhibition space. Allocation based on a first come, first served basis. Additional space can be purchased upon request at a reduced cost of 300 per square meter. 8 exhibitor registrations. Advertisement Inclusion of one insert for promotional purposes in the Congress bag (Insert of up to 8 A4 pages to be provided by sponsor). Acknowledgment of Sponsorship in the Congress book as "Platinum Sponsor" A color advertisement in the Final Programme/Book of Abstracts Sponsor's logo with hyperlink on Congress website. Inclusion of symposium programme on the Congress website. 13

Gold Sponsorship Package 30,000 Organization of a Satellite Symposium Sponsorship of a Satellite Symposium, for up to 30 minutes. The programme is subject to the approval of the Congress Scientific Committee (Satellites will be allocated on a first come, first served basis ). Includes: Hall rental, standard audio/visual equipment, display table Permission to use the phrase: "Official Satellite Symposium of EAP 2019." Symposium programme and abstracts will be included in the Final Programme (Subject to receipt by publishing deadline). Exhibition Space 12 sqm exhibition space. Allocation based on a first come, first served basis. Additional space can be purchased upon request at a reduced cost of 300 per square meter. 6 exhibitor registrations. Advertisement Inclusion of one insert for promotional purposes in the Congress bag (Insert of up to 8 A4 pages to be provided by sponsor). Acknowledgment of Sponsorship in the Congress book as "Gold Sponsor" A half-page color advertisement in the Final Programme/Book of Abstracts Sponsor's logo with hyperlink on Congress website. Inclusion of symposium programme on the Congress website. 14

Silver Sponsorship Package 15,000 Exhibition Space 12 sqm exhibition space. Allocation based on a first come, first served basis. Additional space can be purchased upon request at a reduced cost of 300 per square meter. 2 exhibitor registrations. Advertisement Inclusion of one insert for promotional purposes in the Congress bag (Insert of up to 8 A4 pages to be provided by sponsor). Acknowledgment of Sponsorship in the Congress book as "Silver Sponsor" A half-page color advertisement in the Final Programme/Book of Abstracts Sponsor's logo with hyperlink on Congress website. Mini Symposium 15,000 Sponsorship of a mini symposium, for up to 60 minutes. The programme is subject to the approval of the Congress Scientific Committee (Mini Symposiums will be allocated on a first come, first served basis ). Includes: Hall rental, standard audio/visual equipment, display table Up to 3 mini symposium slots available in the Scientific Programme Permission to use the phrase: Official Mini Symposium of EAP 2019. Mini Symposium programme will be included in the Final Programme (subject to receipt by publishing deadline). 15

Please note the following for all Satellite Symposia: Special time slots will be designated and allocated on a first come, first served basis. Companies sponsoring the Satellite Symposia may select speakers and topics. In addition to the sponsorship fee, companies sponsoring the Satellite Symposia must cover all speakers' expenses, including registration fees, accommodation and travel expenses. This also applies in case the Symposium speakers have already been invited by the Congress. Speakers Ready Room 7,000 Facilities will be available at the Congress Centre for speakers and abstract presenters to go over their presentations. The Sponsors' name and/or company logo will appear on the signposts for the room Opportunity to provide a Sponsor s mouse pad at each workstation Opportunity to display the Sponsor s logo on screensavers at each workstation Sponsor's logo with hyperlink on Congress website Coffee Breaks Sponsorship of Coffee breaks: One day 10,000 All meeting 20,000 Coffee will be served in the exhibition space during morning and afternoon breaks on each day of the Congress sessions. Sponsorship will be acknowledged as follows: Logo in Congress Programme book Full page advertisement in Congress Programme book Significant branding at the Coffee breaks Sponsor's logo with hyperlink on Congress website Congress bags 7,500 The organizers are in charge of the production of approximately 500 delegate bags. The design of the bags needs to be approved by the sponsoring company. 16

Welcome Reception 30,000 Exclusive Sponsorship of the EAP Congress Welcome Reception. Benefits include: Advertisement Branding/logo in Congress Programme Full page advertisement in Congress Programme Significant branding at the Welcome Reception Sponsor's logo with hyperlink on Congress website Name & logo on menus and Welcome Reception vouchers Option to brand suitable promotional souvenirs at the Welcome Reception 2 complimentary passes to attend the Congress and social functions 50-word acknowledgement on inside front cover of menu Verbal acknowledgement at the event A 100-word Company profile in the Congress Final Programme Disk-on-Key 10,000 USB Flash drive containing all the 2015 Congress abstracts. The USB will be distributed to all participants. Sponsorship will be acknowledged as follows: Exclusive advertisement on the back cover of the USB. The sponsoring company will be entitled to distribute the USB from the company exhibiting booth Logo in Congress Programme book Sponsor's logo with hyperlink on Congress Website Lanyards 5,000 The sponsoring company is responsible for the production of the lanyards The sponsoring company will provide approximately 500 lanyards, on which the Congress and Sponsor s logo will be displayed. The design of the lanyards needs to be approved by the organizers. Congress badges 3,000 A badge will be given to each Congress participant. The Congress and sponsor s logo will be displayed on the badge. The sponsor s logo will be included on the Congress website. 17

Notepads and Pens 2,000 The sponsoring company is responsible for the production of the notepads and pens. The sponsoring company will provide approximately 500 notepads and pens, on which the Congress and Sponsor s logo will be displayed. The design of the notepads and pens needs to be approved by the organizers. Pocket Programme 1,500 Exclusive advertisement on the back cover of the pocket sized programme. Promotional Material (Price Per Insert) 1,000 Inclusion of promotional material, such as leaflets and brochures, in the participants' Congress bags. Please note that the material should be provided by the Sponsor and must be approved by the Secretariat (maximum size A4, maximum 8 pages). Advertisements Full-page colour advertisements are available in the following Congress publications: Final Programme/Abstract Book Back Cover 3,000 Final Programme/Abstract Book Inside Front Cover 2,000 Final Programme/Abstract Book Inside Back Cover 1,500 Final Programme/Abstract Book Internal Page 1,000 Special Requests We are aware that the Sponsorship of any of the above items may not suit your current marketing aims. In this case, we can present you with alternative offers which may be more suitable for you. Please feel free to contact our Industry Manager to discuss your needs. Acknowledgements Please note that all Sponsorship opportunities include: The publication of the Sponsors' logos with hyperlinks on the Congress website Acknowledgement on the Sponsors' boards on-site Acknowledgement in the Sponsors' list in the Final Programme Please forward your company logo (in eps 300dpi format) in both black and white and full color versions to Yziv@paragong.com 18

Sponsorship Application Form and Contract Please complete the following information and return to the Exhibition Manager: Paragon Group Mrs. Yael Ziv 18, Avenue Louis-Casai 1209 Geneva, Switzerland Tel: +41 (0)22 533 0948 Fax: +41 (0)22 580 2953 Email: Yziv@paragong.com We, the undersigned, express our wish to Sponsor the items marked below in accordance with the terms described in the Terms of Agreement" attached herewith. Company Name* Contact Name Address Post/Zip Code Country Telephone Fax Email Web-Site Short company description (max of 100 words) * Name of the company - as you wish it to appear on all acknowledgments. 19

I would like to book the following Sponsorship Items: Item Price Total Name of Company:... Method of Payment: Credit card: Credit card no.: Expiry Date: Card Holder: Type of Card: Bank Transfer: Details will be available in the invoice Bank charges are the responsibility of the payer. Terms and Conditions 50% due with signed contract 50% due by June 1, 2019 The total amount should be received before the opening date of the Congress. Please note that your signature on the application form indicates your acceptance of these terms and conditions. Signature and company stamp... Date... 20

Information for Exhibitors A commercial and professional Exhibition will take place parallel to the Congress hours. We wish to maximize the exhibitors' exposure to the delegates, for this reason, all coffee breaks will be held in the Exhibition area. Dates: 19-22 September, 2019 Set up Times: TBA Exhibition Opening Hours: According to the Congress schedule Dismantling times: TBA Please note that the final Exhibition set up, opening and dismantling schedule will be updated in the Exhibition Technical Manual, available 2 months prior to the Congress date. Exhibition Space The price for Exhibition space only is 400 per square meter with a minimum of 6 sqm. This includes: Two chairs 1 standard electric outlet (plug) 100-word Company profile in the Final Programme 2 Exhibitors badges Get-Together Reception for registered exhibitors Refreshments during coffee breaks and light lunches for 2 exhibitors Cleaning of public areas and gangways **Please note that stand space rental does not include any furniture or stand cleaning. All these services and others will be available to order in the Technical Manual. 21

Booth Decorations Exhibitors are forbidden to extend their booths into the thoroughfare or other areas which were not ordered and paid for by the exhibitor. Allocation of Exhibition Space Space allocation will be made on a first come, first served basis. A completed application form accompanied by advance payment should be mailed or faxed to ensure the reservation of a desired location. Upon the receipt of the application form with the payment, space will be confirmed and an invoice for the balance due will be mailed. Please note that three alternative choices should be clearly indicated on the application form. Space allocations will be made in the order in which the application forms with the payment have been received. Advance payment will be refunded if space is unavailable or if the space offered is not acceptable to exhibitors. Exhibitor Registration All exhibitors are required to be registered and will receive a badge displaying the exhibiting company name. Two exhibitor badges will be given for every 6 sqm booked. Any additional exhibitors will be charged a registration fee. Exhibition Technical Manual A technical manual outlining all the technical aspects of the Exhibition will be sent 2 months prior to the Congress and will include the following: Technical details about the venue Final Exhibition details and information Contractor details 22

Acknowledgements Please note that all Sponsorship opportunities include: The publication of the Sponsors' logos with hyperlinks on the Congress website Acknowledgement on the Sponsors' boards on-site Acknowledgement in the Sponsors' list in the Final Programme Please forward your company logo (in eps 300dpi format) in both black and white and full color versions to Yziv@paragong.com 23

Exhibition Application Form and Contract Please complete the following information and return to the Exhibition Manager: Paragon Group Mrs. Yael Ziv 18, Avenue Louis-Casai 1209 Geneva, Switzerland Tel: +41 (0)22 533 0948 Fax: +41 (0)22 5802 953 (Ext. 208) Email: Yziv@paragong.com Company Name* Contact Name Address Post/Zip Code Country Telephone Fax Email Website Short company description (max of 100 words) * Name of the company - as you wish it to appear in all acknowledgments. We would hereby wish to book an exhibition space, the cost of which is 400 per square meter for space only. Choice Stand No Open space ( 400 per sqm) No. of sqm Total Price 1 st Choice 2 nd Choice 3 rd Choice 24

This is a provisional booking. Please hold for 14 days. Payment has been made by transfer, please forward me final confirmation and invoice. Please send me a first deposit invoice for 50% of the total amount due. Name of Company: Method of Payment: Credit card: Credit card no.: Expiry Date: Type of Card: Card Holder: Bank Transfer Details will be available in the invoice Bank charges are the responsibility of the payer. Terms and Conditions 50% due with signed contract 50% due by June 1, 2019 The total amount should be received before the opening date of the Congress. Please note that your signature on the application form indicates your acceptance of these terms and conditions. Signature and company Stamp...Date... 25