Case KG Doc 671 Filed 08/02/18 Page 1 of 2 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE. Chapter 11

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Case 18-10518-KG Doc 671 Filed 08/02/18 Page 1 of 2 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE In re: OREXIGEN THERAPEUTICS, INC., Debtor. 1 Chapter 11 Case No. 18-10518 (KG) RE: D.I. 485, 662 CERTIFICATION OF COUNSEL REGARDING FIRST SUPPLEMENTAL ORDER (I) AUTHORIZING THE DEBTOR TO REJECT CERTAIN CONTRACTS AND (II) GRANTING CERTAIN RELATED RELIEF The undersigned counsel to the above-captioned debtor and debtor-in-possession (the Debtor ) hereby certifies as follows: WHEREAS, on July 31, 2018, the Court entered the Omnibus Order (I) Authorizing the Debtor to Reject Certain Contracts and Unexpired Leases and (II) Granting Certain Related Relief (D.I. 662) (the Omnibus Rejection Order ). WHEREAS, due to an inadvertent error, Exhibit A to the Omnibus Rejection Order omitted twenty-one contracts that were listed on Exhibit A to the Debtor s Tenth Omnibus Motion for Entry of an Order (I) Authorizing the Debtor to Reject Certain Contracts and (II) Granting Certain Related Relief (the Tenth Rejection Motion ) to be rejected by the Debtor, effective as of July 27, 2018 (the Closing Date ). Attached hereto as Exhibit 1 is a form of Supplemental Order (I) Authorizing the Debtor to Reject Certain Contracts and (II) Granting Certain Related Relief (the Supplemental Rejection Order ), which provides that the twenty-one contracts listed on Exhibit A to the Supplemental Rejection Order are rejected by the Debtor, effective as of July 27, 2018 (the Closing Date ). 1 The last four digits of the Debtor s federal tax identification number are 8822. The Debtor s mailing address for purposes of this Chapter 11 Case is 3344 North Torrey,,.

Case 18-10518-KG Doc 671 Filed 08/02/18 Page 2 of 2 WHEREFORE, the Debtors respectfully request that the Court enter the Supplemental Rejection Order at its earliest convenience. Dated: August 2, 2018 Wilmington, Delaware MORRIS, NICHOLS, ARSHT & TUNNELL LLP /s/ Tamara K. Mann Robert J. Dehney (No. 3578) Andrew R. Remming (No. 5120) Tamara K. Mann (No. 5643) 1201 N. Market St., 16th Floor P.O. Box 1347 Wilmington, DE 19899-1347 Telephone: (302) 658-9200 Facsimile: (302) 658-3989 rdehney@mnat.com aremming@mnat.com tmann@mnat.com - and Christopher R. Donoho, III (admitted pro hac vice) Christopher R. Bryant (admitted pro hac vice) John D. Beck (admitted pro hac vice) HOGAN LOVELLS US LLP 875 Third Avenue New York, NY 10022 Telephone: (212) 918-3000 Facsimile: (212) 918-3100 chris.donoho@hoganlovells.com christopher.bryant@hoganlovells.com john.beck@hoganlovells.com Counsel for Debtor and Debtor in Possession 12093477.1 2

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 1 of 6 Exhibit 1

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 2 of 6 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE In re: OREXIGEN THERAPEUTICS, INC., Debtor. 1 Chapter 11 Case No. 18-10518 (KG) RE: D.I. 485, 662 FIRST SUPPLEMENTAL ORDER (I) AUTHORIZING THE DEBTOR TO REJECT CERTAIN CONTRACTS AND (II) GRANTING CERTAIN RELATED RELIEF This matter coming before the Court on the Debtor s Tenth Omnibus Motion for Entry of an Order (I) Authorizing the Debtor to Reject Certain Contracts and (II) Granting Certain Related Relief (the Motion ) 2 filed by the above-captioned debtor and debtor in possession (the Debtor ); the Court having reviewed the Motion; the Court having found that (i) the Court has jurisdiction over this matter pursuant to 28 U.S.C. 157 and 1334 and the Amended Standing Order of Reference from the United States District Court for the District of Delaware, dated February 29, 2012, (ii) venue is proper in this district pursuant to 28 U.S.C. 1408 and 1409, (ii) this is a core proceeding pursuant to 28 U.S.C. 157(b), (iv) that this Court may enter a final order consistent with Article III of the United States Constitution; and (v) notice of the Motion and the Hearing was sufficient under the circumstances; after due deliberation the Court having determined that the relief requested in the Motion is necessary and essential for the administration of the Debtor s estate and such relief is in the best interests of the Debtor, its estate and its creditors; and good and sufficient cause having been shown; IT IS HEREBY ORDERED THAT: 1. The Motion is GRANTED; 1 The last four digits of the Debtor s federal tax identification number are 8822. The Debtor s mailing address for purposes of this Chapter 11 Case is 3344 North Torrey,,. 2 Capitalized terms not defined herein are defined in the Motion.

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 3 of 6 2. Pursuant to sections 105(a) and 365(a) of the Bankruptcy Code, the Contracts listed on Exhibit A hereto are hereby rejected by the Debtor, effective as of July 27, 2018 (the Closing Date ); 3. Notwithstanding the relief granted herein and any actions taken hereunder, nothing in the Motion or this Order shall: (i) constitute an admission as to the validity or priority of any claim against the Debtor; (ii) constitute a waiver of the Debtor s rights to dispute any claim; or (iii) prejudice the Debtor s rights to assert that any of the Contracts are not executory or unexpired within the meaning of section 365 of the Bankruptcy Code; enforceable upon its entry; 4. The terms and conditions of this order shall be immediately effective and 5. The rejection of the Contracts complies with the requirements of Bankruptcy Rule 6006(f); and 6. This Court shall retain jurisdiction to hear and determine all matters arising from or related to the implementation of this order. Dated:, 2018 Wilmington, Delaware THE HONORABLE KEVIN GROSS UNITED STATES BANKRUPTCY JUDGE 2

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 4 of 6 Exhibit A

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 5 of 6 Lease (Lessor) / Contract Counterparty Julie Miller Jumpstart Biodevelopment JW Marrior Washington, DC Kalexsyn, Inc. Kantar Health LLC Kantar Health LLC Baumbach Biancalana Biancalana Biancalana Busenberg Wylie Kathleen J. Day & Associates, LLC Kathleen J. Day & Associates, LLC Kathleen Retterson Kathlyn Racette Kathlyn Racette Kathlyn Racette Lease (Lessor) / Contract Counterparty Address 11067 SE Rimrock Dr. 151 Upper Terrance 1331 Pennsylvania Avenue NW 4717 Campus Drive Suite 800 11 Madison Avenue 12th Floor 11 Madison Avenue 12th Floor 1104 Sea Village Drive 375 Airport Drive 2848 Ash St. 6665 Summit View Drive 6665 Summit View Drive 247 East Street Lease (Lessor) / Contract Counterparty City, State, Zip Happy Valley, OR 97086 San Francisco, CA 94117 Washington, D.C. 20004-1710 Kalamazoo, MI 49008 New York, NY 10010 New York, NY 10010 Cardiff, CA 92007 Worcester, MA 01602 San Diego, CA 92102 Holland, MI 49423 Holland, MI 49423 Lexington, MA 02420 Lease / Contract Title Equity Agreements Re: with Orexigen Therapeutics, Inc. Lease / Contract Effective Date Contract / Lease Type 6/15/2008 Sales Agreement N/A Master Services Agreement 12/7/2006 Stand Alone Service Agreement - HCP Tracker Stand Alone Service Agreement - IDI 4/26/2017 4/26/2017 12/21/2007 Employment Letter Retention Agreement Equity Agreements Terms and Conditions of Service Amendment No. 1 to Orexigen Therapeutics, Inc. Amendment No. 1 to Orexigen Therapeutics, Inc. 7/10/2009 3/31/2016 1/19/2010 1/19/2010 8/3/2011 Employment Letter Retention Agreement Equity Agreements

Case 18-10518-KG Doc 671-1 Filed 08/02/18 Page 6 of 6 Keith Anderson Kejia Shan Kejia Shan 15022 Cross Stone Dr 17141 Silver Pine Road 17141 Silver Pine Road San Diego, CA 92127 San Diego, CA 92127 San Diego, CA 92127 Amendment No. 1 to 2/1/2012 10/21/2017 Amendment No. 1 to 2/27/2018